“1 Billion Cells, 1 Lot, 1 Week”
– Cell Applications and StemoniX Accelerate Life Science Research with Mass Production of Human Induced Pluripotent Stem Cells
Cell Applications, Inc. and StemoniX announced a partnership that will allow them to produce up to one billion human induced pluripotent stem cells (HiPSC) from one lot within one week. These high-quality, consistent stem cells enable researchers to minimize their time laboriously preparing cells and spend more time doing meaningful, relevant research. This achievement was made possible through a proprietary, high-volume manufacturing process that produces affordable, reliable HiPSC for life science discovery.
“The manual process of expanding stem cells is labor intensive and time consuming. By mastering high-volume biomanufacturing, we seek to revolutionize cell-based research and drug screening, leading to a new era of drug discovery and personalized, precision medicine,” said Ping Yeh, StemoniX chief executive officer and co-founder. “Working with Cell Applications, we bring researchers access to high-volume, cost-effective HiPSC to help accelerate the understanding of various diseases and to identify potential compounds to treat them.”
Lab workers at universities, life science institutes and pharmaceutical companies use HiPSC for basic cell biology research and genetic disease modeling, as well as for drug screening, development, efficacy and toxicity assessment. HiPSC typically are generated from adult human tissues—usually skin cells—that can be reprogrammed to an embryonic stem cell-like state thus avoiding the ethical considerations associated with human embryonic stem cells. Being donor/patient-specific, HiPSC open tremendous possibilities for a wide variety of personalized studies in biomedical research. High-volume biomanufacturing also has the potential to change the research paradigm by enabling investigators to save critical time and research dollars. These benefits will be realized by using HiPSC early in the discovery process to assess safety and efficacy issues of drug compounds in-vitro, rather than relying on costly, later-stage methods.
“Cell Applications is pleased that our strategic partnership with StemoniX will facilitate large-scale HiPSC production and enable more research labs, regardless of size, to afford the large cell amounts and consistent quality necessary to advance scientific research,” said James Yu, Ph.D., co-founder and chief executive officer, Cell Applications.
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